06-reference / transcripts

moonshots ep80 mark hyman longevity transcript

Wed Jan 10 2024 19:00:00 GMT-0500 (Eastern Standard Time) ·source: Peter H. Diamandis (YouTube)

if you could tell somebody one thing to do to make a change in their life right now what would that be I think there’s one thing that people need to understand is that aging is a phenomena has been ignored we focus on the diseases that happen as we get older but we haven’t actually studied well the process of aging and if it’s something that we can do something about could you go back to that earlier state of the right genes on and the right genes off if we address those systematically with diet exercise sleep uh Stress Management reduction Community relationships certain biomolecules whether they’re phytochemicals or Pharmaceuticals that we actually have right now today I believe we can most of us get to in our 90s and 100 hi everybody Peter Dand is here welcome to moonshots I’m here with Dr Mark Heyman uh who is just an

[00:01:00] extraordinary human being first and foremost Mark a pleasure to see you pal thank you thank you thank you Peter thanks for having me back you know it’s it’s you have these people in your life that you just love um and you like hanging out with them it’s just like they could do no evil or harm but they’re just you know they lift your spirits and you’re one of those individuals for me yeah and so when you’re in I know you’re the birkar now when you’re back in La well we’re moving La Peter so I’ll I’ll going to be bothering you a lot awesome awesome so are you still are you still in love my friend oh my God love is the best drug it’s the best drug uh you know I I I was there on one of your first dates with your fiance I think yeah well first of all you were a huge Idol for her and I remember I remember you know you you have said this thing around about taking a a trip on one of their zero gravity flights and it was one of her dreams to do that and and you were an idol and I called I called you and I said hey Peter you know like can we go on your thing you’re like yeah we got some space I

[00:02:01] looked there I said you want to go and she like her eyes bugged out of her head she’s like it was like two dreams come true at once meeting you and going into zero gravity I I just you know and by the way you should look at her WhatsApp profile because literally her WhatsApp picture is her sitting in a meditation posure in the middle of the air while she’s a zero gravity on the plane oh my god um what I remember was just you the two of you just were inseparable it was this level of between you know young that young love I I hope you have that for for a century to come my friend and yeah zerog g is an amazing experience i’ I’ve done God knows um probably 50 60 flights on that airplane and it’s uh it’s the only way to really simulate weightlessness uh in the atmosphere on the earth it’s a it’s a parabolic Arc uh and my one of my highlights in my life was flying uh Professor Steven Hawking into zogg you know the world’s expert in gravity into

[00:03:01] into zero gravity and that was a that was a medical um uh that was a risky maneuver and you know I’ve talked about this publicly but uh you know when when we flew him uh the FDA not FDA the FAA said you know you can’t do that you can’t fly you can only fly able-bodied humans and I said well who determines whether they’re able-bodied and uh and they said well his physician or an AOS Bas doctor so I got a few doctors to write letters cuz he wanted to experience zerog G and uh we did eight arcs he had 8 30 second periods of weightlessness but we had set up an emergency room on the airplane we had uh three or four doctors two nurses because you know he was very osteoporotic you know easily break a bone puncture a lung and so we’re super gentle with him but he did it he loved it it was a highlight for me and and as he and his daughter

[00:04:01] Luci said highlight for him as well so um that was fun but not pry intense when you’re when you’re when you’re stuck on the floor and your gravity is pulling you it’s it’s it’s an intense stress on your body it’s amazing you can handle that it is you’re you’re you’re pulling out uh the airplane is basically doing this giant sine wave in the atmosphere um and you begin you know straight level flight uh and then you do a slight nose down to pick up speed and then the airplane pulls up at a 45° angle and during that pull up um you’re at 1.8 gravity so if you weighed 100 lb you’re now weighing 180 lb and then as you push over the top of the arc um centripetal force is pushing your body up gravity is pulling your body down and if the pilot is flying the perfect trajectory where the velocity and the radius I can write up the physics for you here but is perfect you’re in a Arc of an orbit and

[00:05:01] you’re weightless inside the middle so you go from 1.8 gravity to zero gravity and and sometimes we do lunar gravities and Martian gravities which are fun as well so um but you know one of my reasons for being interested in longevity is so I can be around an extra 30 50 100 years to see us on the moon you know and go to build colonies and asteroid belt one of the question I don’t if you’re going to have to wait that long because Peter you know all this uh with all this talk about aliens and all this interesting stuff coming out there may be an alien spaceship that’ll just pop you over it’ll be easy well listen every night when I go to sleep um I say my prayer that if they’re out there please come and get me I’d like to go home they are trust me they are they are I I’ve talk to people literally seen alien spaceships who are astronauts in person so I you have seen them no I’ve talked to someone who was

[00:06:01] was a Black Ops astronaut who went to recover an alien spaceship that was in orbit and saw it himself like well listen I and this guy’s not kind of a crazy whack job either he’s not I that gives me great hope you know honestly I I think life is ubiquitous in the universe you know it’s interesting when you when you stop and think about the numbers you know we are so uh egotistical as human beings we look at um you know what we have in our town in our country on our planet but I don’t know if you know the numbers you you how many uh stars in our galaxy I think I used to know it was like it’s 100 billion billions billions I took astronomy with Carl Sean but that was like 50 years ago I miss him I miss him um yeah 100 billion G uh stars in our galaxy and what’s fascinating is the number of galaxies in the universe M so

[00:07:01] uh the number used to be 100 billion galaxies in the universe it’s now up so somewhere between 2 and 20 trillion galaxies each with 100 billion stars and if you do the math um for my my physics or chemistry Geeks out there uh it’s there at one point I saw the numbers and I and it said huh it’s about like 6 * 10 23rd it’s like avagadro’s number worth of uh uh of stars in the known universe and then of course there are those who claim that we’re living in a Multiverse of an infinite number of universes so um if you’re feeling down don’t worry about it uh so I you know I do want to go and and see what it’s like to you know start a city on the moon or go to the asteroid belt and one of the questions I ask my abundance members often is what would you do in the extra 30 years of life because I think we’re going to be able you know I just launched this $101 million Health span

[00:08:01] prize with xprize uh asking for an extra 20 years of health and those extra 20 years buy you the next 20 years so what what would you do Mark with an extra 20 or 30 healthy years of life you know for me at this point in my life Peter it’s a great question I I kind of climbed all the mountains you know there’s a great book by David Brooks called the second Mountain which is once you’ve you know had your family built your career got your financial stability then what right I’m in the then what phase which is basically in service giving back and and providing the value that I’ve learned over my life back to the world and and for me it’s it’s really you know both in terms of the work I’m going to do which is sort of scaling up the the framework of our new understanding of human health and biology which you could call Network medicine functional medicine whatever you want to call it it’s just going to be called medicine and the second is really you know deepening my own personal development and growth and healing you know in in the in the the Hindu tradition there’s

[00:09:00] this whole concept of the householder who then goes through this process of being a householder which is essentially the first mountain and then they go and become a sasin which is a Wandering kind of wise guy basically where they they they they are seeking out a deeper spiritual Evolution and I think for me that’s very important to kind of deepen my sense of self uh my my sense of relation with myself with my fiance and partner with with my friends in community and with the people I care and love about so it’s it’s really being more leaning into that and of course having a hell of a good time while doing it yes AB white said I think he said uh he said every day wake up uh determined to uh make the world a better place and have a hell of a good time and that makes planning the day very difficult you know I I I think bringing joy to life is so important you know I’ve I’ve gotten know Elon really well over 20 plus years and um he’s absolutely brilliant but he’s his own

[00:10:01] worst enemy in terms of uh the level of stress and work and he puts it on himself uh and so you know I think about that you know what you know humanity is a beneficiary for from SpaceX and from Tesla uh and and from X um but you know at what price do you do this and and life work balance is an interesting term it’s part of um it’s part of that longevity conversation I remember having this conversation with with Tony Robbins on stage and Tony goes no no no there’s no such thing is life work balance it’s integration uh and if you love what you do um which you do and I do and hopefully those listening to then it’s not you’re not working you’re playing um and and that’s I I was looking at a tweet from venod kosla who said um you know working 80 hours a week and plan to do that and continue investing for the

[00:11:01] next 25 years and I was like huh I wonder how much I work and I either don’t work at all or I work all the time depending on on how your definition is yeah yeah yeah so um you know let’s talk get into the the meat of the conversation I have a a number of of questions from my my I’m going to still call it a Twitter audience but uh and some vegetables as it may be um so you know one of the conversations out there is aging a disease um and if so why right and uh you know I think it would be super convenient to call aging a disease so that we had the ability for it to be funded from government you know Government research and so forth um do you have any opinion about this yeah absolutely I mean I think you know Peter what we’ve seen historically in medicine is that aging as a phenomena has been ignored we focus on the diseases that

[00:12:00] happen as we get older but we haven’t actually studied well the process of aging and if it’s something that we can do something about and I I think also we see an inevitability as we get older we see people who are frail and weak and decrepit and declining and loss of function and inability to do the normal things they want to do but that’s not necessarily an inevitable part of getting older or it’s it’s a process of decrepitude that is a result of fundamental biological processes that go wrong that we can do something about just like we can treat blood pressure or cholesterol or blood sugar the phenomena of of abnormal aging which is what I think most of us have in this country and around the world increasingly is a treatable condition and and I I’ve seen this over and over in my patients whether they’re at endstage diseases or whether they’re just looking for a tuneup I’ve seen people both feel and look younger by applying the science of creating health so I mean yes and even

[00:13:02] though we’re doing that we still are getting older and dying and there’s nobody living past 120 that at least I know of I mean there may be some Himalayan monks who claim that yeah exactly but so the question I’ve always asked myself and I’ve asked uh George uh George church and David Sinclair this question like is there an upper limit to human age you you know can we make it to 150 can we make it to 2 or 300 you know not as we are today but with the right genetic engineering and the right cellular therapies or or others am curious where you come out on that do you do you do you is it religion do you hope do you have a sense to say no it’s impossible no I mean I I I first of all the question of immortality and extending life and immortality

[00:14:00] that that’s a that’s more of like a a kind of spiritual philosophical question about like what what what would you do with all that time but I think in terms of the the the science I I think if we appli what we know now about the fundamental things that cause damage to what we call the Hallmarks of aging and and and drive these biological processes that underly all of disease heart disease cancer diabetes dementia all the disease of Aging if if we address those systematic Ally with diet exercise sleep U Stress Management reduction Community relationships certain biomolecules whether they’re phytochemicals or Pharmaceuticals that we actually have right now today in 2023 soon to be 24 I believe we can most of us get to in our 990s and 100 I don’t think that’s beyond reach for most people I I do think that getting to 120 or 150 or 180 is a whole different ball game and I think there’s some regenta therapies that may help uh

[00:15:00] whether they’re things like you know exomes or peptides or stem cells or plasmapharesis which are really interesting I don’t know if those are going to get us much more Runway they might get a little bit more they might improve health span more but I I think there are some scientific things coming down the pike that are really interesting and and are not ready for prime time and I think one of the most important ones is the discovery of the amanaka factors which you’re right about in life force and and this is this is being studied by David Sinclair others in animal models and seeing really kind of remarkable results but the basic idea is that we can reprogram our own cells back to a younger version of themselves in sort of a simplistic way of looking at it it’s by inserting uh very various transcription factors into your genome you can turn them on or off at will and when you hit let’s say 50 if you’ve had these inserted 25 and you say I’m getting a little flabby my muscle wasting my hair is gray and I don’t have the same sex drive and whatever you can

[00:16:00] just turn this on through some molecular switch and then reverse your biological age now that’s still a TBD right I think we don’t know it is you know the conversation I have with with George and David is is uh and I’m I’m curious to bring bring that into this conversation because it’s important I mean people need to have a goal to shoot for and I think the goal right now is uh keep yourself as healthy as you can intercept the breakthroughs from the yamanaka factors epigenic reprogramming all of that I mean when a when when you are you know 30 or 40 or 50 as a guy um and in your 20s and 30s as a woman typically and you reproduce that egg is set at a zero age and it can live an entire full life the data is there for a for continuation um at the same time you know iind people when you’re true think just to kind of reemphasize what you’re saying if a 40-year-old man and a 40y

[00:17:00] woman have sex and they have a 40-year-old sperm and a 40-year-old egg the baby’s not 40 years old when it’s born it’s zero yeah it’s zero so so the potential is there um and then the other thing I I point out to folks is listen you’ve got the same 3.2 billion letters from your mother and your father when you’re born when you’re 20 when you’re 80 when you’re 100 why do you look different and it’s not the code it’s not your genome it’s which genes are on which genes are off it’s your epigenome and if can you could you go back to that earlier state of the right jeans on and the right jeans off of earlier so you get that six-pack when you’re when you’re you know in your in your 70s or 80s and so this is the conversation and then you know it’s the other idea that is thrown out is you know this is my grandfather’s old Hatchet it’s got four new handles and five new heads but it’s my grandfather’s old Hatchet uh you know can you just keep replacing parts yeah I mean I think that’s the other thing

[00:18:00] that’s coming down the pike is replacement parts right we can 3D print organs we can you know from your own cells basically grow a new heart or grow a new liver I mean this is happening and I I think you’ve been talking about this in many of your conferences and workshops and I I think it’s it’s kind of exciting I mean I I don’t want to be the first one to get it but I think it’s gonna it’s G to it’s going to come soon and the reason it’s coming even faster I think is more capital is coming into the field than ever before right there’s billions of dollars of private Capital coming in uh because you still can’t take it with you no matter how high you tried um because ultimately uh there’s more people playing in this field the tools are getting more powerful and cheaper and AI is coming into the rescue so you know I think we’re going to see some massive massive changes if you could tell somebody one thing to do to make a change in their life right now what would that be I mean you know it

[00:19:01] reminds me of um this conference I was at when some I asked the same question to a longevity scientist lard gu guy from MIT who basically came up with David Sinclair with the idea of the cin and I and it was this conference with the dama and Longevity and it was Western scientist Elizabeth Blackburn was there and Lenny was there and and uh Dal Lama was there and all these Tibetan doctors and I was walking with Lenn I was like so what is the secret here what what is the secret with these CER and what is the deal he says what’s making us Age and what what’s the problem he’s like sugar and I’m like what he’s like yeah sugar and I think I think there’s one thing that people need to understand is that one of the main I think meta categories of the Hallmarks of Aging is deregulated nutrient sensing which has to do with how our bodies sense food and when that becomes screwed up because of too much or too little of something our bodies become disregulated and all the Hallmarks get accelerated all of them and I think the most important insulin signaling pathway there is the one

[00:20:01] that’s driving a lot of the disease of Aging so if you look at heart disease cancer diabetes dementia they’re all diseases of too much insulin and insulin resistance and that’s all driven by the enormous loads of sugar and starch we eat you know I was recently Peter in Africa and I got to visit the hasabe tribe which is the last remaining Hunter gather tribe that’s protected in Africa and they continue to hunt and 20% of their diet is honey and I’m like geez that’s a lot of sugar and and what I also learned was that and I I went gathering with them and we hunted and gathered a little bit together and they they were you know digging up these roots and and tubers and they eat 150 grams of fiber a day that’s compared to about eight eight grams for the average americ which the the uptake in the reaction basically it’s like yes basically putting minam musil in your Coca-Cola basically but but it but it mitigates the effect of the sugar so I think it’s just the enormous amounts of shars and sugar that are driving all these aging Pathways and they drive inflammation they drive oxitive stress they damage

[00:21:00] your mitochondria microbiome it’s it’s the one thing if you can cut out starch and sugar or dramatically reduce it it’s going to have a huge impact everybody I want to take a short break from our episode to talk about a company that’s very important to me and could actually save your life or the life of someone that you love company is called Fountain life and it’s a company I started years ago with Tony Robbins and a group of very talented Physicians you know most of us don’t actually know what’s going on in inside our body we’re all optimists until that day when you have a pain in your side you go to the physician or the emergency room and they say listen I’m sorry to tell you this but you have this stage three or four going on and you know it didn’t start that morning it probably was a problem that’s been going on for some time but because we never look we don’t find out so what we built at Fountain life was the world’s most advanced diagnostic Centers we have four across the us today and we’re building 20 around the world

[00:22:01] these centers give you a full body MRI a brain a brain vasculature an AI enabled coronary CT looking for soft plaque a dexa scan a Grail blood cancer test a full executive blood workup it’s the most advanced workup you’ll ever receive 150 gabt of data that then go to our AIS and our physicians to find any disease at the very beginning when it’s solvable you’re going to find out eventually you might as well find out when you can take action Fountain life also has an entire side of Therapeutics we look around the world for the most Advanced Therapeutics that can add 10 20 healthy years to your life and we provide them to you at our centers so if this is of interest to you please go and check it out go to Fountain life.com Peter when Tony and I wrote Our New York Times bestseller life force we had 30,000 people reach out to us for

[00:23:00] Fountain life memberships if you go to Fountain life.com back/ Peter will’ll put you to the top of the list really it’s something that is um for me one of the most important things I offer my entire family the CEOs of my companies my friends it’s a chance to really add decades onto our healthy lifespans go to fountainlife decom Peter it’s one of the most important things I can offer to you as one of my listeners all right let’s go back to our episode sugar is a poison remove it from your diet the body was never designed to deal with this much sugar and we’re living in a day and age where unfortunately our food manufacturers are pumping out you know poison the same way our cigarette manufacturers are were pumping out poison well they were they were the same companies you know that Peter like Philip Morris CFT RJR Nabisco they they actually redesign the foods when they own those companies they now have kind of divested but but when they the tobacco opening companies own the food companies they redesigned the the foods to be more addictive that comes to a

[00:24:00] question that uh enus um sarak one of my followers asked here he says how do you deal with the emotional challenges of sugar addiction so to be clear sugar is and you’re you get addicted to Sugar um and it’s uh it takes time uh to get off of that addiction uh and I I do that by the way uh enus with my you know abundance community every year we do a 22-day no sugar fast as a group we all do it together we just give it all up um and uh once you’ve gone through that uh process you have more control how do you think about it it’s an emotional issue well yes and no I mean I think I think people think it is uh and and sometimes it is uh and it’s physiological issue it’s complex right because there’s there’s genetics involved and dopamine receptors and your your uh risk of becoming more addictive when it comes to

[00:25:00] sugar or other substances there’s the way that Sugar hijacks your hormones your brain chemistry even your microbiome to regulate your mood your appetite your behavior and a lot of times people misappropriate their emotional state to some psychological reason as opposed to a physiological reason and I I think you know most of us have the experience like if we’re you know if our blood sugar low we’re cranky right if we’re if we’re haven’t eaten it’s not because we’re mean irritable cranky people it’s because there’s a physiological reason so I think I think it’s important for to understand that it sometimes there are emotional reasons for eating it’s stress and various kinds of things like Comfort Foods as they call comfort food for sure for sure but but but what’s what’s important to understand is that you need to use science not willpower to actually overcome this and I wrote a book in 2014 called the 10day detox diet the blood sugar solution 10day detox diet and the idea is you know if you you follow a regimented approach to resetting your hormones and brain chemistry in your microbiome you can get off of it very

[00:26:02] quickly and not deal with the consequences it usually takes about 2 or 3 days to go through it but if you but if you do the right things you don’t suffer as much so you got to start the day with protein and fat you got to actually eat plenty of fiber you’ve got to have lots of fluids and liquid because when you drop sugar your body’s going to dump a lot of fluid and and because insulin keeps you retaining salt and so you retain a lot of water and and then you need to make sure you do things with your nervous system to calm your nervous system down and I you know take an Epsom salt bath and gentle exercise and you know really doing Simple practices and and I’ve done this with people over and over groups and and online thousands of people and it’s remarkable how quickly the body resets it doesn’t take that long now you know it’s like it’s like if you’re if you you kind of have to go cold turkey if you don’t you you’re going to kind of just be constantly just in this Dynamic of stimulating the wrong pathways so it it’s there is an emotional aspect but

[00:27:01] there’s also an understanding and for example you can look at your genetics and look at dopamine receptor genetics and see if you’re one of those people who really needs a lot of extra stimulation for dopamine which then you can learn how to activate like a cold plch if you jump on an ice bath I guarantee you it’s gonna wake you right off and it’s going to stimulate your dopamine and and I love doing that it’s sometimes I forget how long I’m in there and I come out and I’m like shaking but but uh definitely feels great after it feels great yeah it feels great and and there’s really a physiological process to reset so it’s not that hard but you have to understand what to do and how to do it and how to re-regulate your hormones and brain chemistry and then you can see where you’re at and then you know but if you’re if you’re sleep deprived that’s the other thing if you’re sleep deprived and they’ve done this in college students where they’ve looked at at healthy college students of normal weight and they gave them uh basically normal sleep schedule or they were deprived of like you know a couple extra hours of sleep so they had eight or six or 5 hours and the ones who had

[00:28:00] sleep deprivation all were craving sugar and carbs and I remember this from being in the in internship and residency and delivering babies up all night working in the ER and I’m like it was like 2 a.m. and I was like where is the sugar like I’m going to McDonald’s and because the only thing open in the hospital by the way having McDonald’s in the hospital is ridiculous but it was only I would get what was apple turnovers that was my that was my thing so I get the apple turnover and then keep going for the rest of the night yeah oh my God yeah no it’s a listen in medical school by the way those of you who are thinking about going to medical school those who had been in medical school it is like the worst possible uh you know set of of uh operating protocols for help I mean doctors are terrible in terms of Sleepless the diets we eat taking the stress that levels that you have um yeah uh so you know let’s take a second to explain to folks why glucose is such an inflammatory molecule right uh how it it’s glycating and how

[00:29:01] it’s you know in in the brain in the heart would you would you walk through that a second yeah so so the couple things happen like it’s just a whole Cascade so you know when you when you have high insulin levels it drives uh your glucose into your cells and also any every extra calorie right so it drives free fatty acids and other things into your fat cells and particularly your belly fat and those are the dangerous fat cells and and those fat cells aren’t like normal fat cells on your butt or your legs they’re they’re metabolically active they’re hormonal factories they’re neurotransmitter factories they’re immune factories and they’re spewing out all this nasty stuff including cyto kindes and hormones that disregulated your appetite and so they make you hungry they make you put on more weight and they prevent what we call lipolysis which is the breakdown of fat so it’s it’s like a one-way Turn Style in the subway you can get in but you can’t get out and and essentially that’s what’s going on with insulin and then once you start this this visceral fat um Factory of bad stuff that bad stuff

[00:30:02] drives inflammation and you get high levels of inflammation cyto kindes and inflammation is is kind of the final common pathway of all age related diseases whether it’s dementia heart disease diabetes cancer obviously autoimmune disease aging itself has been called inflammaging and so it drives a lot of that process the secondary things that happen is that it it is part of that you get damage to proteins and one of the one of the main phenomena in terms of the Hallmarks of Aging is something called proteostasis which is damage to our proteins and proteins have to be particularly shape size and and in threedimensional structure uh to work and what happens is you get glaming on of sugar and proteins together when there’s too much sugar and it causes thing called glycation which is basically like a crispy skin on chicken or a crust on a bread or creme brulee that crispy thing on the top that’s stuff that you love to eat that tast you to eat now those are called Advanced glycation end products and are ages and

[00:31:02] it’s a good terminology because they age you and they bind to rages which makes you rage and and basically get aged um and that leads to again the secondary phenomena of more inflammation and so one you have damaged proteins they don’t work two it creates a Cascade of more inflammation and you end up in this vicious cycle and the way we measure for example people with diabetes is something called hemoglobin A1c that’s glycosilated hemoglobin it means hemoglobin your basically oxygen carrying molecule in your red cells gets sugar on it and forms a crust and that crust basically makes it not work well and then you get into all these secondary problems and and that really is is a huge phenomen of aging and we can avoid ages in our food too by not microwaving by you know not over over cooking stuff by not having the crispy stuff which we love I mean I still eat it occasionally make a roast chicken and I I go after the skin I get to cut it up because I cooked it and I get those little you’re making me hungry

[00:32:01] dude oh so I just want people to realize you know sugar is a it’s a very you know as it is like you said glomming on to the to the proteins and your immune system recognizes that as a foreign entity and you hit an inflammatory Cascade it’s it hits the heart it hits the brain it hits the body in general and it’s just um do yourself the favor of uh breaking that sugar addiction if at all possible uh your your book on that subject the name of it again 10day detox diet 10day and and uh you know the Beautiful the beautiful thing is it you know probably hasn’t changed since in the last in last decade so it’s relevant go get it and and try it you’ll owe yourself getting yourself off sugar um you know what I want to say is Peter just to to emphasize that people don’t realize how bad they feel until they start feeling good and and I have people fill out a questionnaire it’s in the

[00:33:01] book where they they give a qual quantitative score to all their symptoms you know headaches digestive issues sleep problems depression snotty nose whatever and you get a score and then after 10 days you redo it the average reduction in the score was 70% from all symptoms from all diseases and I do this over and over when I do workshops I’m doing a longevity Workshop in baa in May another one in in uh Bodrum in Turkey in May at six censes uh and and and I do the same diet there and it’s it’s just remarkable what happens people walk away feeling amazing and they didn’t realize how quickly can happen and guess what it’s all within your control it doesn’t cost anything if anything you’re going to save money on the process you know one of the things I I I put in um in my recent book longevity or practical Playbook and and we’ve talked about this before is even the order which you eat your food uh matters right um eating your fiber first eating your veggies

[00:34:00] first so that it slows down digestion eating your protein next and then saving any uh high glycemic carbs uh for the end if you have room um and just doing that alone uh causes your digestive system to uptake the nutritious molecules first and and minimizes your insulin Spike from you know the white rice or the bread that you’re going to be or The God forbid the dessert you’re going to eat at the end yeah everybody Peter D madis here uh I’ve been asked over and over again what do I do for my own health well I put it down in this book called Peter’s longevity practices uh it’s very readable in just an hour in the book I cover longevity diet exercise sleep my annual found upload meds and supplements longevity mindset it’s literally consumable in just an hour’s time hopefully to incentivize you to make a difference in your life to intercept the technology coming our way if you want this just check out the link below and download it right now um a lot

[00:35:00] of people are dealing with this uh with OIC gp1 uh Inhibitors and such um I I’m curious what you’re hearing about OIC you know it’s like everybody I know is on OIC and it’s like you know the most all of a sudden it became the most popular drug out there yeah I think it’s the biggest part of the G the GDP of Denmark right now is the zic because it’s a Danish company um yeah I I know Peter it it can help certain people and I’m I’m not opposed to its uh appropriate use and the appropriate person for the appropriate amount of time in the right way but I I think like like many many drugs uh the New England Journal uh basically came out with a great article once they said make sure you use new drugs as soon as they come on the market before the side effects develop and I think that’s kind of the situation we’re starting to see now we’re seeing you know benefits for people who struggle but I’ve seen people who are you know 10 20 15 pounds overweight starting to use this it’s I think it’s it’s risky one it it it causes uh a significant amount of muscle

[00:36:00] loss as you lose weight and you already lose muscle when you lose weight but it seems to be worse and then you end up actually with a lower muscle mass at a lower weight which actually means your metabolism is slower so often um what happens and with with weight zic we see this 65% or more uh of the weight is gained back if you stop it you will end up having a slower metabolism at the end of the process than when you started so let’s say you start at 220 lbs you lost 30 lbs then you gained back a bunch of pounds you’re going to have a slower metabolism and have to eat less to just maintain that 2 20 pounds at the end second it it seems to increase the risk of certain GI problems which I really concerns me and it’s not just an incremental increase we’ve talked about this before but essentially when we see a you know a a change in a result in a in a scientific study of 20 30% so statins reduced the risk of heart attack by 20 or 30% that sounds like a lot okay that’s not that

[00:37:03] much when you look at the effect of these zic drugs there’s we’re seeing a 900% increase in a pancreatitis a 450% increase in small B obstruction which is a very serious disease this is problem where you need surgery or hospitalization to deal with the B obstruction because it thickens the wall of your bowel and it happens when you’ve been taking it for a longer period of time so you might see rapid results but I think I think it just kind of misses the point of why are we struggling in the first place you know I I I went again I I mentioned I went to Africa and and I I didn’t see anybody who was overweight in these Hunter gathered tribes there was nobody not a single person uh you know when you look at pictures of America and I I remember seeing this artha Franklin movie it was from 1970 it was in Oakland where she filmed it it was an incredible film about called Amazing Grace or something and and uh you know it was in a black church in Oakland there was not one

[00:38:01] overweight person including arthra in that movie who was in the church and this was 1970 and now you know 85% of African women are overweight H rates of diabetes let’s let’s let’s dive there one second what is the cause is it our food system is it a lack of what what has changed in the last 40 years here well I think we never had the degree of ultra processed foods and I think it’s becoming clear and clear that this phenomenon of ult processed foods is at the root of so much of what’s going on of course our life styles become more sedentary we’ve had more stress there’s more environmental toxins our microbiomes change there’s a lot of variables but but I think the big fundamental biggest change is the introduction of all ultr processed food there’s over 600,000 of these on the market now and and what what they are not really Foods they’re deconstructed food- like products so essentially when you take a soybean or a corn cob or or a wheat berry you eat those you’re fine it’s fine but if you

[00:39:02] if you take them into a factory and you deconstruct them into their molecular parts and then you reorganize the molecular structure so they’re not even recognizable in their original form and then you reassemble them into all kinds of sizes colors and shapes of chemical extruded food likee substances that look like food but aren’t food they actually don’t regulate your body in the same way and and Kevin Hall did this really impressive study he’s from the looking at Ultra processed food it was a crossover trial where he took people and fed them as much as they want of regular Whole Foods they just eat as much as you want no limit go for it and then he said here’s Ultra processed food eat as much you want no limit go for it the people had the ultra processed food ate 500 calories more a day now in a week that’s 3500 calories 3500 calories is what it takes to gain a pound so in a year that’s 52 pounds of weight gain just from eating if you eat Ultra processed food oversize me baby yeah and and so

[00:40:03] it’s it’s really been a problem and we know the mortality risk is high it causes depression it causes mood destabilization inflammation uh it changes your microbiome and I I think we’ve seen this this horrific change in our food system and supply and of course there’s the you know just the uh o overabundance of calories in our system as well I mean we’ve seen you know in in in 1970s ear President Nixon was a afraid of not getting re-elected because the price of milk and meat were going up so he told his a secretary to fix it and basically what he did was incentivized Farmers to grow massive amounts by giving subsidies and and essentially created a model of accelerated industrial Agriculture and high fructose corn syrup and now we produce 500 calories more of of corn essentially turned into corn sugar and syrup than we did before so there’s another 500 calories to day in the food supply per person Captain Crunch Captain Crunch is here to save us I mean it’s like I you know I have two 12-year-old boys and I think about the

[00:41:01] food that they eat and it’s oh my God oh my God so listen I was just on I saw on on Twitter um yesterday a gentleman whose ID was kept confidential who’s experimented with a a fost Statin uh criser edit and uh someone in their 40s 50s and all of a sudden gained a huge amount of muscle right so um have you seen any of this uh work going on yeah I mean I’ve been reading about it I think it’s a little bit sci-fi and and there’s been studies for example in muscular distrophy that improves for example ambulation and and muscle strength and function so for certain conditions I think you know if you have musco distrophy and you’re going to in a wheelchair and die I think it’s go for it you know but I think I’m not ready to start taking it yet I think we need I think a lot more human trials for it but it it has even started really in that regard but I’m I am interested in um uh

[00:42:02] in the concept of beginning to engineer ourselves you know someone who I known for a long time uh haven’t been in touch lately is uh is Brian Johnson um I knew him from uh he was an investor in a couple my companies early on uh have you been followed what he’s doing with the blueprint yeah it’s very fascinating I mean he’s he’s basically measuring and tracking every single thing he can possibly think of and then seeing the effects of various changes in his lifestyle diet supplements behaviors and how those impact his his biology and I I I would give him credit because he’s basically taken one for the team he’s like I want to be a human experiment and I want to see how far I can push this and how long I can live and and basically do do science a favor by spending my own millions of dollars uh with an N ofone experiment on myself and I think I think we’re going to learn a

[00:43:00] lot from that I I do think it makes for a pretty dull guy to be around I mean his last meal is 11 o’clock at night in the morning I mean he goes to bed at 8:00 at night and I’m like okay and you know he says well sometimes I break out and I’m kind of you know just don’t want to be socially kind of weird so I’ll I’ll go out to dinner and I’ll eat some steamed vegetables and I’m like well okay I don’t know if that does a trick Brian but yeah I mean it’s a it’s like I can’t have anybody sleep in bed with me you know I can’t I can’t be in a relationship I can’t like you know it’s like well those are things that are really important you know uh if you’re in a relationship and you have good social connections it’s probably one of the things that impacts longevity the most so I wouldn’t miss on that one you know he um one of the things he’s famously done is uh received transfusions from his son and offered transfusions you know the whole Young Blood experiment work out there uh thoughts on that well this is really you

[00:44:01] know kind of an extrapolation of research that was done on mice called parabiosis where they basically wired up the old mice and the young mice circulation to see what would happen and they found that the old mice became young now they weren’t sure the young mice became old old right and so they weren’t sure what it was so they actually followed up on some of these studies and they they actually did a plasma exchange where they basically did a filter of the old mouse blood so instead of just getting young blood they just took out all the old plasma which has all the inflammatory molecules damage proteins things that you know are kind of accelerating aging and then just remove them and it had the same benefit now this is not a new thing I I want to make this very clear the the just taking out the old plasma and putting in instead albumin and saline which is the you know the fluid segment of the plasma had the rejuvenative effect uh of a

[00:45:00] plasmic exchange yeah fascinating it’s fasc and and they’ve done some interesting studies like that that are on humans and Alzheimer’s patients and seeing remarkable results and improvements of their cognition and activities of daily living and by the way there’s no drug that can do what the plasma does I mean it’s it’s quite it’s quite amazing that we’re we’re seeing these sort of level of results that are in a pretty Advanced disease Dr zipro yeah Dr zipro I guess has the has the protocols there and uh at F we’ve just installed uh this therapeutic plasma exchange uh technology so our members can go and and start doing that yeah I’ve done it you’ve done it as well how often do you recommend doing it well I don’t think we know the frequency yet but I I I’m I probably would like to do it every quarter I I think it’s a sort of a just a tuneup you know it’s like an oil filter change right and I I actually one time I did it you know if you feel good you know I say if you don’t have a headache and aspirin doesn’t do much so you know might might do something subclinically or Sub sub perceptually but it’s not going to affect you right

[00:46:01] so I’ve had plasma exchange when I feel fine and I I I definitely feel a boost of energy and well-being and you know more subjective things but once I had covid and I was really sick and I and I it was the worst Co I’d had I had it like three times and I and I developed arthritis after my hands SW swelled up I had severe fatigue I was just really incapacitated and I was worried you know and I ended up going having plasmapheresis and literally within hours my swelling went away in my hand my joints became normal the next morning I felt like a million bucks and I was like wow there’s something to this you know because we use it in medicine already we use it for people with autoimmune diseases with inflammatory diseases with neurologic diseases with G Amber syndrome with vaccine injury so it’s used a lot for people who have and and by the way I’ve seen people with covid vaccine injury and I’m send them for plasma recess and they do remarkably well so it takes out all the inflammatory guck basically in your system that’s a medical word right Peter gck

[00:47:00] yes we learned about that yeah um so a lot of people uh have desired to go get stem cells after reading life force and of course in the United States uh stem cell uh from placental stem cells or cord stem cells allergenic from somebody else or is not legal today um and what you need to do is get you can get stem cells from your own bone marrow your own fat and you can concentrate them and and give them back to yourself um and or you can go down to uh uh Costa Rica uh rmis down there or uh you know Mexico there’s a number of different locations South of the Border you can go and get uh get stem cells uh what’s your thinking today on stem cells well uh full disclosure I’m going down in N9 days to RMI for a full stem cell treatment so what I’m doing is I heavy stem cells uh I’m doing Orthopedic stem cells in my back and uh my knee I I

[00:48:02] jumped off a golf cart trying to save my girlfriend she fell off and banged her head and I twisted my knee and got a little meniscal thing I’m doing my knee uh uh I’m going to do the sexual enhancement one because I’m 64 why not and uh do the skin Rejuvenation and soort of just do the whole thing and I’ll give you a report afterwards but I’ve done uh systemic Sim cells uh I think three times I’ve done once in my knee for a knee injury and and I found it incredibly helpful um I think you felt a visceral change you felt functional change yeah I definitely felt overall more energy more clarity uh Improvement of My overall uh you know Fitness so I I did I did notice certain things now they’re subjective I didn’t have any objective metrics uh and I’m I’m going to do this again I’m going to recheck my biological age after so I’ve been tracking it and I’m getting some biomarkers done before and after so I I’m I’m curious about it I think you know we definitely need more data I’m I’m like you Peter I I’m definitely on the Leading Edge of things and I I wouldn’t recommend the things that I’m doing to myself to my patients sometimes

[00:49:01] but but I’m willing to take one for the team Chief get Chief guinea pig yes yeah yeah so I I think I I study it I think about it and it sounds that their scientific basis if if the risks are low and something that’s I can afford I’ll do it and and uh and and that’s kind of how I play the game but I I think it’s really about your risk tolerance and and I think what we need is a large infusion of capital into a research in clinical trials using stem cells from everything from you know longevity to autoimmune diseases to um you know Orthopedic issues I mean we just we just have so many applications for these and I think we’re unfortunately just so behind on this yeah no it’s it is unfortunate it’s not uh something that the FDA has the proper guidelines to regulate yet and so it is sort of just kept in the don’t do it category uh we are standing up at Fountain under a investigation new drug

[00:50:01] protocol um placental dve stem cells the other area that we’re standing up uh with our sister company cellularity that Bob hurri who’s my dear friend um is natural killer cell supplementation so um people should know you know natural killer cells are your innate immune system that detects cancer uh detects scile cells detects uh infected cells and as we age like your body’s pack yeah exactly exactly uh as we age our immune system goes becomes you know dysfunctional disregulated and so uh the results we’ve seen early on with natural killer cells uh where you can give it as a exo from an exogenous Source placental derive Source um looks super promising so I think that’s going to be another indd where we give people people um natural killer cells to help uh address

[00:51:02] building up of ccent cells in the body yeah i’ I’ve done that too I’ve done it actually for my own cells I Dro 20 botes of blood sent it to a lab that was cultured had to go to a different country to do it but but basically I did the infusion of my own natural killer cells as well so you know I think it’s hard to kind of say what these things do and and again this is sort of experimental but I think that these things are all all things that need to be more rigorously studied and there is there is data it’s just it’s just slow and plotting and I think we need to put Capital into this because it can it can help people with so many different conditions hey everyone I want to take a quick break from this episode to tell you about a health product that I love and that I use every day in fact I use it twice a day it seeds ds01 daily symbiotic hopefully by now you understand that your microbiome and your gut health are one of the most important modifiable parts of your Health you know your gut microbiome is connected to everything your brain health your

[00:52:00] cardiac health your metabolic health so the question is what are you doing to optimize your gut let me take a moment to tell you about what I’m doing every day I take two capsules of seeds ds01 daily symbiotic it’s a two-in-one probiotic and Prebiotic formulation that supports digested Health gut health skin Health heart health and more it contains 24 clinically and scientifically proven probiotic strains that are delivered in a patented capsule that actually protects the contents from your stomach acid and ensures that 100% of it is survivable reaching your colon now if you want to try seed’s ds01 daily symbiotic for yourself you can get 25% off your first month supply by using the code Peter 25 at checkout just go to seed.com moonshots and enter the code Peter 25 at checkout that’s seed.com moonshots and use the code Peter 25 to get your 25% off the first month of

[00:53:01] seeds daily symbiotic trust me your gut will thank you all right let’s go back to the episode yeah I mean sarcopenia is you know whenever I I have a venture fund bold Capital I’m actually in their offices right now and uh uh I tell people if you’ve got a we’re now probably 2third biotech Health Tech I say if you’ve got a uh a company that addresses sarcopenia I want to hear about it right I think it’s one of the biggest challenges we have the loss of functional muscle tissue and and muscle strength as we as we grow old um you know the numbers uh even better than I if you if you fall and and fracture your hip um there’s a damn good chance you’re not going to make it out of the hospital um and so you know having the ability to regain and or maintain muscle mass in your 70s 80s 90s is super critical what do you do what do you think about um besides a a crisper Gene edit

[00:54:03] uh what what do you recommend for somebody what’s your protocol for maintaining and growing muscle mass well well you know I think uh i’ I’ve double down on as I’ve got older and and essentially I I focused on a regular strength training routine three or four sometimes five times a week with bands and weights if I have them available I then uh focus on my protein intake which is a basically a a gram of protein per pound for me that’s about 175 to 180 gram so that’s what I do as well and then I I make sure that I and this is really important to understand for people is that you know people talk intermittent fasting well okay you you probably should not eat for 12 hours between dinner and breakfast that’s just called breakfast know like you eat dinner at 6 you can eat breakfast at 6 it’s not exactly fasting right if you eat dinner at 8 you can eat breakfast at 8 uh maybe 14 hours but when you when you’re

[00:55:00] fasted and it’s important I think to do at least a 12-hour overnight fast the first meal really matters because it’s not just the fasting that that it’s important that induces um activation of mtor or inhibition of mtor and autophagy or self-cleaning like your self-cleaning oven it’s the first meal that you have after you do that that’s critical because that first meal determines what happens next and what happens next if you do it right meaning right being having 40 to 50 grams of protein when you do that then it activates mour but it also does it in a way that synthesizes muscle protein or muscle protein synthesis and it activates your stem cells it activates all these longevity Pathways so it’s it’s got a sort of kind of a dual benefit so it’s it’s both the feeding fasting and the feeding that matter and the feeding has to’s your breakfast so for example this morning I woke up early I was kind of up early I did some meditation and wrote my journal for a

[00:56:00] bit then I went for about an hour and a half hike up mountain behind my house came back did a 30 minute rigorous band workout um did some stretching and then you know took a a quick steam and a nice bath and then I had my my shake and my my call my healthy aging Shake I’m happy to give you the recipe you can it’s in my book actually young forever and you can you can check it out but essentially I take goat whey and whey protein is is more well tolerated by my most people some people the dairy is a little hard it’s regenera raised goway and it’s about 40 50 grams I put in mitop pure which is urethan a I use Mito pure as well yeah and I use a th000 milligrams and urethan a the date on this is really impressive it it induces mitochondrial synthesis mitochondrial biogenesis induces mitophagy improves uh RIS it reduces sarcopenia and and improves muscle synthesis as well as also reducing inflammation and many many other really impressive things I also

[00:57:00] add in 5 grams of creatine to help muscle building uh and I put a bunch of other stuff in there uh which which isn’t necessar for muscle building but I’ll put in adaptogenic mushrooms I’ll put in my gut food product which essentially has pre probiotics and polyphenols uh what else I put in there uh I I sometimes put in other other immunoglobulines for my gut and gut healing probiotics and so that that’s kind of my morning shake and I’ll put in some almond milk or or maybe Macadamia milk and some frozen berries and that’s basically my shake and I don’t have it’s no it’s not sweeten it doesn’t have any sugar uh and and the berries give a nice flavor and make it like like a milkshake love it that is so close to I do do you I I I’ve enjoyed kachava as well as a uh as a drink yeah the thing the thing that’s important is make sure you know plant-based proteins can be great but you have to make sure that they’re they’re they’re they’re the right um B of amino acids and and as you get

[00:58:00] older you get anabolic resistance meaning it’s harder to build muscle and and the great limiting amino acid for activating mtor which builds muscle is Lucine so if you don’t have two and a half grams of Lucine in a serving of protein that you’re having you’re not actually switching on the the the switch to build the muscle so you can add Lucine you can add you know you can actually add a scoop of Branch amino acids or you can take something called amino acid complex by thorn and I don’t have any relationship with them or any Financial thing with them at all but but this has been well studied it was actually a product that they bought from a European company that was used to treat sarcopenia in elderly and it’s basically an amino acid complex that has high levels of Lucine so you can throw that in your shake if you want but I I would be careful to make sure you you look at the amino acid composition and at least has two and a half grams and and goat way versus uh versus grass-fed beef well gra you know if you have you know the thing is if it’s grassfed grass finished okay that’s fine but what kind

[00:59:01] of cow is it is an A2 cow or is an A1 cow so A2 casine is is less inflammatory it’s like gersy gery and Jersey cows and other heirloom cows oras most cows in America are holing cows and they’re all A1 casine which is super inflammatory creates a lot of risk issues that I I’m concerned about and most way doesn’t have that much casine but it’ll have a little and I think I notice for example when I have because I’m I’m sensitive to Dairy it’s one of the foods that I’m just sensitive to if I have I do not I do not eat dairy if yeah if I if I have like whey protein like somewhere I’ll be somewhere I just want to think I’ll have a whey protein I’ll notice my nose gets all congested and I have I’m flemy and if I do a podcast it’s terrible but but but if I have the goat way I don’t have any of that so I know there’s something going on where it’s triggering some immune inflammatory response when I have regular regular way you said um you know 12 hours you should you should fast these 12 hours um I am curious your reviews on intermittent fasting because you know it was you know

[01:00:01] there’s so much um conversation around you know 18 hours off you know 6 hours on uh you know 20 hours off 4 hours on and you know I was reading that the studies actually don’t show that that makes a difference and what really matters is your total caloric intake sure can you speak to that yeah for sure well it it does give you a little bit time more for autophagy and I think I think having at least 12 hours is is minimum and not that’s not really a fast it’s just normal it’s like you shouldn’t you shouldn’t eat before bed and you can eat when you wake up it’s basically in America we just keep eating until we have dinner then we after dinner snacks then we have a snack before bed we have a second dinner that’s that that’s just terrible for you it’s really bad uh it’ll make you gain weight basically it’s I call the Suma wrestler diet is what I wrote about in one of my first books called Ultram metabolism how do the Summa wrestlers gain so much weight they’re normal little Japanese guys well

[01:01:00] they they basically feed him enormous calorie dense food and then they make them go take a nap and then they wake them up and they do exercise and they have another huge meal and then they take another nap so basically they they go to sleep so it’s basically you eat on full stomach is the way they gain weight uh but I think inter intermittent fasting can be challenging because if you do it you can lose muscle and then you end up you know in kind of a counterproductive Ive state so I think it’s really individual if you’re very overweight and you want to use it as a strategy to drop a bunch of weight I think it’s great I think if you’re for someone like you know you and I who are mostly metabolically optimized I I think extended extended fasting probably is not a great idea because the reason I the reason I stopped as well is because I’m trying to you can’t load all of your protein at one sitting um your body is not going to absorb it and so I like to spread you know my 150 g uh including a you know a breakfast when I cuz I work out first thing in the

[01:02:00] morning so it helps me make sure I get protein breakfast lunch and and dinner um I’m curious total calories what’s your view on caloric intake I think it’s really important I think you know we we excess calories are not good and and I how much do you suggest a person eat how much do you eat it depends right so it depends on your metabolic engine right if you’re someone’s been on OIC and you’ve lost all this muscle and you’re you know 180 lbs like me you’re probably going to need far less calories than I do because you know my V2 Max is high I have high muscle mass I have very low body fat so I need a lot of calories I need like almost 3,000 calories a day but but if if you um are someone who’s not as active if you’re someone who’s you know not metabolically tuned up then you may need less calories so it really depends on your body type and you can do measurements of your basil metabolic rate uh with various kinds of devices

[01:03:00] now you can do it in a lab where they measure oxygen and carbon dioxide exchange we used to do that when I worked at Canyon Ranch and you can see you know it’s usually basically uh the way to figure it out is is 10 times your body weight in calories so if you’re 180 pounds like me my basil metabolic rate is 1800 calories and then for your activities of daily living you usually add on another 30% right so 30% on top of that would be like 2400 calories so that’s basically my basic needs now if I’m like going for a five uh hour bike ride right or I’m climbing up the ever bace camp where I you know like like I did this summer and was hiking you know 10 miles at 14,000 ft straight up I might need more so it it depends on what you’re doing but that’s basically kind of how you figure it out and by the way calories as a way of thinking about looking at your food just is kind of a hopeless Endeavor if you take the Top

[01:04:01] nutritional scientists who study calories and you tell them okay I want you to determine the calorie count of the food you ate without actually like measuring it and weighing it and everything they won’t be able to do it and and if you’re off by 100 calories a day like just 100 calories a day which is not very much it’s like a bite of food you’re going to gain like 20 pounds in a year right so you know what you have to understand is it’s really about regulating your metabolic system so that your brain chemistry your hormones and your metabolism are all working in Synergy so that you’re going to self-regulate and do it in a way that that is your body is smart and knows what to do because if you try to count calories it’s kind of forget it you know a question from from my uh my Twitter audience here says what real-time metrics do you look at to track longevity and you know it’s interesting I wish there were good metrics I mean you know true age uh as a

[01:05:01] as a you know your methylation clock interesting um and since it’s the only real thing I think there is out there uh I measure that but I measure percent by you know fat and and muscle mass and things like that what do you measure well it’s important to think of like what are the risk factors and then what are the what are the actual measurements of biological age and I’ll send you a paper after we get off that kind of looks at all the different biological age clocks and there’s a number of them and there’s number of inferential ones for example Morgan leine has you know used a number of different epigenetic markers than for example the hor Horvath clock which is more or less what’s used for true age and and what they vary minute to minute day to day in the same person they can vary decade to decade by different tests even with the same person in the same time so um she she’s calculated based on some simple blood biomarkers whether it’s Al in you know Red Cell distribution of width CRP glucose alos which a lot of markers that

[01:06:02] don’t exactly make sense to me for biological age but apparently it it’s pretty reliably uh calculated to correlate with a lot of the epigenetic marks so it’s sort of a it’s sort of an you know uses large data sets to come up with uh a kind of a a surrogate way of measuring these epigenetic marks using regular blood tests and I think it’s interesting but the question is what do you do with those well you have to find one and or you can use multiple and then change your lifestyle or habits or supplements and then check it again as a way of sort of being your own control but but the real the real things I look at are blood biomarkers Imaging biomarkers to see what’s really going on in the body and and from a functional medicine perspective I’m actually giving a talk on Friday at the buck Institute of aging on longevity Diagnostics and it’s really about what are the things we we should be looking at and from a functional perspective I think about how do we assess Health not just what are we’re looking for disease and I I do

[01:07:00] that too but but I do the gallery screen to look for cancer biomarkers and liquid biopsy or I’ll do the clearly heart scan to look at AOS scerotic plaque whether it’s soft or hard plaque and that that’s all looking for actual disease but I’m also looking for um where the trajectory of people are from from from Wellness to illness right there’s a there’s a it’s not it’s not a like a on or off phenomenon it’s a Continuum of shifts and change in your biological systems so we look at the your bio your your microbiome and your gut and the health of that we look at the various immune biomarkers we look at your mitochondrial function we look at detoxification and and toxic load we look at the health of your your vascular and lymphatic system your communication networks from hormones to neurotransmitters to peptides to cyto kindes and we look at your structural system and there’s various biomarkers you can look at all those and then we look at the fundamental things like you know nutritional status you know we look at muscle mass and fat Mass we look

[01:08:00] at V2 max testing we look at uh inflammatory markers and so we can get a real sense of what’s going on in the body and I co-founded a company called function Health which gives you access to over 110 biomarkers for five less than 500 bucks that you can get check twice a year it’s a membership model and and it’s amazing people what we found we’ve had over 20,000 people go through we’ve had over a million biomarkers tested and the things we’re finding are just shocking because this is a health forward population and we’re seeing you know 95% with the part LDL particle number problems 89% with small LDL we’re seeing 51% with high APO B which is a big risk factor for heart disease we’re seeing 30% with high Ana which is an autoimmune marker 46% with high CRP we’re like 20% with severe vitam deficiency it’s like amazing right so if you don’t look you don’t see it and and by the way um you know functional medicine what function health is doing what Fountain is doing both of them

[01:09:01] based on on fun on functional medicine is you know root cause it is uh nothing I ever learned about in medical school but it is the most important um you know basis uh for I for me for choosing a position yeah well I mean they’re the only ones thinking about the network effect of everything that’s happening in your body I mean the body is a network and and when you go the doctor they’re focused on a reductionist disease-based model and so you’re you’re such a super specialist and it’s amazing to me how how limited training is when you’re an XY or Z specialist you really have no clue about anything else and it’s just like I’m like wow well the body is a system so how do you treat one thing without thinking of everything I I just can’t do that my brain doesn’t work that way I see everything together I’m like okay well here’s the hierarchy of problems here’s the hierarchy of solutions let’s get going you know well buddy listen list um first of all I take great um great joy and confidence in

[01:10:01] knowing that our diet our sleep plan our exercise plan our Supplement Plan our met plan is very similar it’s very Sim that’s great I love that I love that yeah and uh I’m also excited you’re moving to LA and third when you when you get here I’m open for a sunrise walk on the beach here all right down awesome awesome well listen P thank you so much uh for for for joining me on moonshots again and as always grateful for you and my life and me too and thanks for what you’re doing Peter just to make the world a better place you’re a big Force for good thank you buddy be well I want to take a moment to tell you about abundance 360 my yearround leadership Mastermind for people who want to go big create wealth and impact the world it’s also Singularity University’s highest level program a key focus of abundance 360 is helping my members develop their massive transform of purpose or MTP and also to Define and execute on their

[01:11:01] moonshots you’re listening to the moonshot podcast so question is do you have an MTP do you have your own moonshot for example my massive transformative purpose my MTP is to inspire and guide entrepreneurs just like you to help you create a hopeful compelling and abundant future for Humanity my MTP drives everything I do it guides me it inspires me my books my companies the X prises we launch it’s all born out of that MTP as an entrepreneur you need to have an MTP it’s your highest level aspiration it connects your emotional drive with the moonshots you take on your MTP drives the direction of your moonshot it allows you to pursue your grandest dreams it fuels you to go 10x bigger and impact the world so the question is where do you go to discover C your MTP to hone your moonshot join me at abundance 360

[01:12:00] it’s a global community of World Changers entrepreneurs investors philanthropists all of whom have an MTP and the moonshot we support each other in making indent in the universe to posibly uplift Humanity our mission at a360 is to give you the tools the network and the inspiration to go big again to create wealth and to uplift Humanity if hearing this has you thinking I want to be part of that I need someone to help support my MTP and moonshot then consider joining us submit your application at a30c that’s a36c see you there now back to our [Music] podcast