Weekly Dose of Optimism #175

Curation of five optimism-forward stories from science and technology.

Curated Topics

1. New Food Pyramid — National Design Studio publishes updated food pyramid correcting decades of flawed dietary guidance favoring carbs over fats
2. Grey Market Peptides — Deep dive on Chinese peptides, GLP-1s, and gen-3 weight loss drugs; grey market semaglutide at $50/mo vs $24K brand-name
3. Boltz Lab Platform — Open-source AI models for biomolecular design; $28M seed from a16z and Amplify Bio
4. General Matter HALEU Contract — $900M DOE contract for domestic uranium enrichment capacity; nuclear momentum accelerating
5. Jacob Rintamaki on Robots — Technical/economic analysis of robotics future; robots-and-data-centers flywheel thesis

RDCO-Relevant Items

• Boltz Lab: AI agents for scientific discovery, open-source model strategy
• HALEU/nuclear: energy infrastructure for AI compute
• Robotics flywheel: data infrastructure implications of robot-built AI infrastructure